Nutraceuticals & Alternative Medicine
GC-VUV provides unambiguous identification and quantitation of alternative medicine contaminants and adulterants. Compounds are unambiguously identified and quantitated, and software automation makes data analysis accessible to users of all skill levels.
Known advantages of VUV Spectroscopy
- Provides both qualitative and quantitative characterization of alternative medicine and related contaminants
- The capability of characterizing isomeric impurities without need for chromatographic baseline resolution
- Software deconvolution of analyte co-elution allows short GC chromatographic compression
- Intuitive data processing workflow and software automation remove analytical complexity
- Robust instrumentation with minimal maintenance needs
- Easy to understand analysis by Beer-Lambert Law (same principle used in UV-Vis spectroscopy)
SEE THE LATEST ABOUT NUTRACEUTICAL & ALTERNATIVE MEDICINE ANALYSIS BY GC-VUV
Learn more about how GC-VUV can provide rapid screening of pesticides and environmental contaminants. See how VUV spectroscopy delivers more accurate analyte identification and quantitation.
Solving Analytical Challenges in Nutraceuticals & Alternative Medicine
Key Features of VUV Spectroscopy
- High degree of data analysis automation reduces human error
- Intuitive spectral fingerprint compound identification and Beer’s Law quantitation eliminates guesswork
- Software deconvolution of co-eluting analytes allows chromatography runtimes to be deliberately compressed
- Proprietary algorithms automate compound class characterization
Shining a new light in gas chromatography and streaming gas applications.
Everything absorbs strongly in the VUV spectrum. Compounds can be unambiguously identified and quantitated in a variety of applications including oil & gas, forensics, fragrances & flavors, petrochemical, environmental, and life science. VUV detectors provide unmatched selectivity of isomers and co-eluting analytes without the need for chromatographic baseline resolution. Unlike legacy detection methods, VUV spectroscopy allows for more automated analysis with lower risk of errors, shorter chromatography run times, and higher analytical throughput.
- Universal, yet selective detector with very sensitive spectral response
- Easy deconvolution and quantitation of co‑eluting analytes
- Robust technology with no reliance on vacuum pumps
- No calibration required – 1st principle detection technique provides a predictable linear response
- Complements mass spectrometry by fully characterizing isomers and compounds with low mass quant ions
Coeluting Peaks and VUV Absorbance Spectra – When a Little Means a LotJack Cochran, VUV Analytics
Jack Cochran, VUV Analytics
As a gas chromatographer using MS the coeluting-isomer problem didn’t bother me too much, as it allowed me to practice the art of separation. Inevitably though, critical compound separation leads to undesirable, longer GC run times, which brings us back to VUV and its uniqueness.
The LCGC Blog: Time Interval Deconvolution as an Alternate Strategy to Peak Integration Using Gas Chromatography–Vacuum Ultraviolet Spectroscopy[LCGC Blog]: Dr. Kevin A. Schug, University of Texas, Arlington
The LCGC Blog: Time Interval Deconvolution as an Alternate Strategy to Peak Integration Using Gas Chromatography–Vacuum Ultraviolet Spectroscopy
[LCGC Blog]: Dr. Kevin A. Schug, University of Texas, Arlington
In this LCGC blog, Dr. Kevin Schug describes rapid Time Interval Deconvolution (TID) data analysis and how it is applied to PCBs and gasoline samples.
An Interview with Dr. Nicholas Snow About Gas Chromatography and VUV SpectroscopyPaul Johnson, VUV Analytics
Paul Johnson, VUV Analytics
VUV Analytics recently announced Dr. Nicholas Snow as the recipient of their summer 2016 academic grant, which provides Dr. Snow’s laboratory with the use of the VGA-100 Vacuum Ultraviolet (VUV) detector to do novel research on gas chromatography.
Discriminating Isomers and Isotopologues using Gas Chromatography – Vacuum Ultraviolet SpectroscopyDr. Kevin A. Schug, et al., University of Texas, Arlington
Dr. Kevin A. Schug, et al., University of Texas, Arlington
Dr. Schug's presentation at ISCC and GCxGC 2017 discusses how Sum Squared Residual values relate to the differentiation of isomers by GC-VUV. Isomer systems investigated include petroleum hydrocarbons, pesticides, fatty acids, polychlorinated biphenyls, designer drugs, and benzene isotopologues.
“The VUV detector has proven itself with the ability to distinguish olefins and aromatics from aliphatics – that’s a killer application given the complexity and time involved using any other technique. The VUV detector’s ability to perform a more accurate and much more robust PIONA analysis is an important milestone in its ongoing success.”
Bill Winniford, Fellow
Bill Winniford, Fellow, The Dow Chemical Company, Houston, Texas, USA
“VUV spectroscopy adds a dimension that is complementary to mass spectrometry, offering selectivity that is difficult to otherwise obtain.”
Hans-Gerd Janssen, Professor and Science Leader
Hans-Gerd Janssen, Professor, University of Amsterdam, and Science leader, Unilever Research Vlaardingen, the Netherlands
“One of the main advantages of VUV detection for us appeared to be the ability to gain more specific molecular information…co-elutions that we know exist but cannot be identified with FID can be unraveled.”
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager, Research & Development, TOTAL Refining & Chemicals, Normandy, France
“The VUV detector will be used as a universal, calibration-free tool that provides the relative quantitative values of distinct molecules in mixtures in a rapid manner.”
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor, University of Messina, Italy
“One thing that I really like about VUV is that it can be considered a universal detector but with the advantage of being familiar to us. We all used UV spectrometers in school.”
Nicholas Snow, Professor
Nicholas Snow, Professor, Seton Hall University, New Jersey, USA
“Eliminates ionization inefficiencies that are encountered in mass spectrometry analysis."
Mark R. Emmett, Ph.D.
Mark R. Emmett, Ph.D. Professor, The University of Texas Medical Branch Galveston, UTMB Cancer Research Center
“An amazingly simple concept extended into a powerful spectral region."
Tim Hossain, Ph.D.
Tim Hossain, Ph.D. Chief Scientist, Cerium Laboratories
“The VUV detector is a powerful new tool in the GC toolbox."
Kevin A. Schug, Ph.D.
Kevin A. Schug, Ph.D. Professor & Shimadzu Distinguished Professor of Analytical Chemistry, The University of Texas at Arlington