Nutraceuticals & Alternative Medicine

GC-VUV provides unambiguous identification and quantitation of alternative medicine contaminants and adulterants. Compounds are unambiguously identified and quantitated, and software automation makes data analysis accessible to users of all skill levels.

Known advantages of VUV Spectroscopy

Provides both qualitative and quantitative characterization of alternative medicine and related contaminants
The capability of characterizing isomeric impurities without need for chromatographic baseline resolution
Software deconvolution of analyte co-elution allows short GC chromatographic compression
Intuitive data processing workflow and software automation remove analytical complexity
Robust instrumentation with minimal maintenance needs
Easy to understand analysis by Beer-Lambert Law (same principle used in UV-Vis spectroscopy)

SEE THE LATEST ABOUT NUTRACEUTICAL & ALTERNATIVE MEDICINE ANALYSIS BY GC-VUV

Learn more about how GC-VUV can provide rapid screening of pesticides and environmental contaminants. See how VUV spectroscopy delivers more accurate analyte identification and quantitation.

Read About the GC-VUV Method for Multiclass Pesticide Analysis

Learn About Classification and Speciation of PCBs in Industrial Mixtures

Read About Rapid TID Data Analysis of Complex Mixtures

Learn About Isomer Differentiation of PCBs

Solving Analytical Challenges in Nutraceuticals & Alternative Medicine

Key Features of VUV Spectroscopy

High degree of data analysis automation reduces human error
Intuitive spectral fingerprint compound identification and Beer’s Law quantitation eliminates guesswork
Software deconvolution of co-eluting analytes allows chromatography runtimes to be deliberately compressed
Proprietary algorithms automate compound class characterization

Spectral Identification

Shining a new light in gas chromatography and streaming gas applications.

Everything absorbs strongly in the VUV spectrum. Compounds can be unambiguously identified and quantitated in a variety of applications including oil & gas, forensics, fragrances & flavors, petrochemical, environmental, and life science. VUV detectors provide unmatched selectivity of isomers and co-eluting analytes without the need for chromatographic baseline resolution. Unlike legacy detection methods, VUV spectroscopy allows for more automated analysis with lower risk of errors, shorter chromatography run times, and higher analytical throughput.

Universal, yet selective detector with very sensitive spectral response
Easy deconvolution and quantitation of co‑eluting analytes
Robust technology with no reliance on vacuum pumps
No calibration required – 1st principle detection technique provides a predictable linear response
Complements mass spectrometry by fully characterizing isomers and compounds with low mass quant ions

PCBs

Blog

Coeluting Peaks and VUV Absorbance Spectra – When a Little Means a Lot

Jack Cochran, VUV Analytics

Publication

The LCGC Blog: Time Interval Deconvolution as an Alternate Strategy to Peak Integration Using Gas Chromatography–Vacuum Ultraviolet Spectroscopy

[LCGC Blog]: Dr. Kevin A. Schug, University of Texas, Arlington

Publication

An Interview with Dr. Nicholas Snow About Gas Chromatography and VUV Spectroscopy

Paul Johnson, VUV Analytics

Technology Overview

Discriminating Isomers and Isotopologues using Gas Chromatography – Vacuum Ultraviolet Spectroscopy

Dr. Kevin A. Schug, et al., University of Texas, Arlington

Enter the Knowledge Base

“The VUV detector has proven itself with the ability to distinguish olefins and aromatics from aliphatics – that’s a killer application given the complexity and time involved using any other technique. The VUV detector’s ability to perform a more accurate and much more robust PIONA analysis is an important milestone in its ongoing success.”
Bill Winniford, Fellow
Bill Winniford, Fellow, The Dow Chemical Company, Houston, Texas, USA
“VUV spectroscopy adds a dimension that is complementary to mass spectrometry, offering selectivity that is difficult to otherwise obtain.”
Hans-Gerd Janssen, Professor and Science Leader
Hans-Gerd Janssen, Professor, University of Amsterdam, and Science leader, Unilever Research Vlaardingen, the Netherlands
“One of the main advantages of VUV detection for us appeared to be the ability to gain more specific molecular information…co-elutions that we know exist but cannot be identified with FID can be unraveled.”
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager, Research & Development, TOTAL Refining & Chemicals, Normandy, France
“The VUV detector will be used as a universal, calibration-free tool that provides the relative quantitative values of distinct molecules in mixtures in a rapid manner.”
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor, University of Messina, Italy
“One thing that I really like about VUV is that it can be considered a universal detector but with the advantage of being familiar to us. We all used UV spectrometers in school.”
Nicholas Snow, Professor
Nicholas Snow, Professor, Seton Hall University, New Jersey, USA
“Eliminates ionization inefficiencies that are encountered in mass spectrometry analysis."
Mark R. Emmett, Ph.D.
Mark R. Emmett, Ph.D. Professor, The University of Texas Medical Branch Galveston, UTMB Cancer Research Center
“An amazingly simple concept extended into a powerful spectral region."
Tim Hossain, Ph.D.
Tim Hossain, Ph.D. Chief Scientist, Cerium Laboratories
“The VUV detector is a powerful new tool in the GC toolbox."
Kevin A. Schug, Ph.D.
Kevin A. Schug, Ph.D. Professor & Shimadzu Distinguished Professor of Analytical Chemistry, The University of Texas at Arlington

Nutraceuticals & Alternative Medicine