Chemical compounds and their precursors can be unambiguously identified and quantitated by VUV spectroscopy. Solvents, water, and other analytes can be characterized in the same run, saving time and analysis complexity.
Known advantages of VUV Spectroscopy
- Provides both qualitative and quantitative characterization of target compounds along with their precursors and contaminants
- The capability of characterizing isomeric impurities without need for chromatographic baseline resolution
- Software deconvolution of analyte co-elution allows short GC chromatographic compression
- Intuitive data processing workflow and software automation remove analytical complexity
- Robust instrumentation with minimal maintenance needs
- Easy to understand analysis by Beer-Lambert Law (same principle used in UV-Vis spectroscopy)
SEE THE LATEST ABOUT SPECIALTY CHEMICAL ANALYSIS BY GC-VUV
Learn more about how GC-VUV can speed up your specialty chemical analysis time while providing more accurate quantitative analysis.
Solving Analytical Challenges in Specialty Chemicals
Key Features of VUV Spectroscopy
- High degree of data analysis automation reduces human error
- Intuitive spectral fingerprint compound identification and Beer’s Law quantitation eliminates guesswork
- Software deconvolution of co-eluting analytes allows chromatography runtimes to be deliberately compressed
- Proprietary algorithms automate compound class characterization
The VGA-101 is a next generation universal detector for GC with extended wavelength and higher allowable operating temperatures. It is intended to simplify complex applications with advanced capabilities including complete isomer identification, shorter GC run times, and resolution of co-eluting peaks.
VUV en Vogue – The Analytical ScientistThe Analytical Scientist
This article in the Feb 2017 edition of The Column describes the results of a pilot study focused on trace water determination in common organic solvents using an ionic liquid stationary phase of GC column in a GC-VUV platform.
Coeluting Peaks and VUV Absorbance Spectra – When a Little Means a LotJack Cochran, VUV Analytics
Jack Cochran, VUV Analytics
As a gas chromatographer using MS the coeluting-isomer problem didn’t bother me too much, as it allowed me to practice the art of separation. Inevitably though, critical compound separation leads to undesirable, longer GC run times, which brings us back to VUV and its uniqueness.
“The VUV detector has proven itself with the ability to distinguish olefins and aromatics from aliphatics – that’s a killer application given the complexity and time involved using any other technique. The VUV detector’s ability to perform a more accurate and much more robust PIONA analysis is an important milestone in its ongoing success.”
Bill Winniford, Fellow
Bill Winniford, Fellow, The Dow Chemical Company, Houston, Texas, USA
“VUV spectroscopy adds a dimension that is complementary to mass spectrometry, offering selectivity that is difficult to otherwise obtain.”
Hans-Gerd Janssen, Professor and Science Leader
Hans-Gerd Janssen, Professor, University of Amsterdam, and Science leader, Unilever Research Vlaardingen, the Netherlands
“One of the main advantages of VUV detection for us appeared to be the ability to gain more specific molecular information…co-elutions that we know exist but cannot be identified with FID can be unraveled.”
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager, Research & Development, TOTAL Refining & Chemicals, Normandy, France
“The VUV detector will be used as a universal, calibration-free tool that provides the relative quantitative values of distinct molecules in mixtures in a rapid manner.”
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor, University of Messina, Italy
“One thing that I really like about VUV is that it can be considered a universal detector but with the advantage of being familiar to us. We all used UV spectrometers in school.”
Nicholas Snow, Professor
Nicholas Snow, Professor, Seton Hall University, New Jersey, USA
“Eliminates ionization inefficiencies that are encountered in mass spectrometry analysis."
Mark R. Emmett, Ph.D.
Mark R. Emmett, Ph.D. Professor, The University of Texas Medical Branch Galveston, UTMB Cancer Research Center
“An amazingly simple concept extended into a powerful spectral region."
Tim Hossain, Ph.D.
Tim Hossain, Ph.D. Chief Scientist, Cerium Laboratories
“The VUV detector is a powerful new tool in the GC toolbox."
Kevin A. Schug, Ph.D.
Kevin A. Schug, Ph.D. Professor & Shimadzu Distinguished Professor of Analytical Chemistry, The University of Texas at Arlington