Gas chromatography is a key tool in the analysis of trace components in high purity gases used at pharmaceutical, electronics, petrochemical, food and beverage plants, and medical facilities, or in support gases for analytical instrumentation in laboratories and research facilities. Mixed gases are also carefully quantified to be used for the calibration of analytical or process instruments.
Known advantages of VUV Spectroscopy
- Provides real-time bulk and specialty gas data, enabling improved process control
- Blended gas samples can be analyzed with one detector that is not dependent on chromatographic separation
- Overlapping signals can be easily deconvolved using VUV software
- Improved sensitivity advantage of 100 – 1000X over FTIR
- Easy to understand analysis by Beer-Lambert Law (same principle used in UV-Vis spectroscopy)
Solving Analytical Challenges in Specialty Gas
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Key Features of VUV Spectroscopy
- High degree of data analysis automation reduces human error
- Intuitive spectral fingerprint compound identification and Beer’s Law quantitation eliminates guesswork
- Software deconvolution of co-eluting analytes allows chromatography runtimes to be deliberately compressed
- Proprietary algorithms automate compound class characterization
Shining a new light in gas chromatography and streaming gas applications.
Everything absorbs strongly in the VUV spectrum. Compounds can be unambiguously identified and quantitated in a variety of applications including oil & gas, forensics, fragrances & flavors, petrochemical, environmental, and life science. VUV detectors provide unmatched selectivity of isomers and co-eluting analytes without the need for chromatographic baseline resolution. Unlike legacy detection methods, VUV spectroscopy allows for more automated analysis with lower risk of errors, shorter chromatography run times, and higher analytical throughput.
- Universal, yet selective detector with very sensitive spectral response
- Easy deconvolution and quantitation of co‑eluting analytes
- Robust technology with no reliance on vacuum pumps
- No calibration required – 1st principle detection technique provides a predictable linear response
- A non-destructive technique that compliments mass spectrometry
Dr. Kevin Schug has extensive experience using the VGA-100 and writes about his discoveries in LCGC. Read the full post for some background on how he got involved with GC-VUV, and his usage of our detector.
Flow-modulated comprehensive two-dimensional gas chromatography combined with a vacuum ultraviolet detector for the analysis of complex mixtures – Journal of Chromatography A
This article is focused on the use of a vacuum ultraviolet absorption spectrometer (VUV) for gas chromatography (GC), within the context of flow modulated comprehensive two-dimensional gas chromatography (FM GC × GC).
The vacuum ultraviolet (VUV) spectrophotometer was developed recently as an alternative to existing gas chromatography detectors. This detector measures the absorption of gas-phase chemical species in the range of 120–240 nm, where all chemical compounds present unique absorption spectra.
Intelligence at the Analytical “Edge”Clark Jernigan, VUV Analytics
Clark Jernigan, VUV Analytics
This is my first ever blog post, so a little grace in advance, please. I’ve been thinking lately about parallels between historical developments in the networking and computing fields and current developments in the analytical chemistry field. Most of us are familiar with the sea changes from mainframes to minicomputers to desktop PC’s to smart...
“The VUV detector has proven itself with the ability to distinguish olefins and aromatics from aliphatics – that’s a killer application given the complexity and time involved using any other technique. The VUV detector’s ability to perform a more accurate and much more robust PIONA analysis is an important milestone in its ongoing success.”
Bill Winniford, Fellow
Bill Winniford, Fellow, The Dow Chemical Company, Houston, Texas, USA
“VUV spectroscopy adds a dimension that is complementary to mass spectrometry, offering selectivity that is difficult to otherwise obtain.”
Hans-Gerd Janssen, Professor and Science Leader
Hans-Gerd Janssen, Professor, University of Amsterdam, and Science leader, Unilever Research Vlaardingen, the Netherlands
“One of the main advantages of VUV detection for us appeared to be the ability to gain more specific molecular information…co-elutions that we know exist but cannot be identified with FID can be unraveled.”
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager
Pierre Giusti, Molecular Separation & Identification Service Manager, and Gaelle Jousset, Gas Chromatography Laboratory Manager, Research & Development, TOTAL Refining & Chemicals, Normandy, France
“The VUV detector will be used as a universal, calibration-free tool that provides the relative quantitative values of distinct molecules in mixtures in a rapid manner.”
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor
Luigi Mondello, Chair of ISCC and GCxGC Conference in Riva del Garda, and Professor, University of Messina, Italy
“One thing that I really like about VUV is that it can be considered a universal detector but with the advantage of being familiar to us. We all used UV spectrometers in school.”
Nicholas Snow, Professor
Nicholas Snow, Professor, Seton Hall University, New Jersey, USA
“Eliminates ionization inefficiencies that are encountered in mass spectrometry analysis."
Mark R. Emmett, Ph.D.
Mark R. Emmett, Ph.D. Professor, The University of Texas Medical Branch Galveston, UTMB Cancer Research Center
“An amazingly simple concept extended into a powerful spectral region."
Tim Hossain, Ph.D.
Tim Hossain, Ph.D. Chief Scientist, Cerium Laboratories
“The VUV detector is a powerful new tool in the GC toolbox."
Kevin A. Schug, Ph.D.
Kevin A. Schug, Ph.D. Professor & Shimadzu Distinguished Professor of Analytical Chemistry, The University of Texas at Arlington