Article Preview
A GC-VUV and automated headspace method for residual solvent analysis in pharmaceutical products results in >5X shorter chromatography runtimes and allows the combination of multiple solvents (Class 1, 2, and others) into a single analysis is described.
Fill out the form below to access VUV Analytic’s Knowledge Base. Stay up to date with the latest VUV blogs, publications, application notes, conference presentations, webinars, and announcements.
Related Reading
TRACE LEVEL ANALYSIS OF NDMA USING GAS CHROMATOGRAPHY AND THE LUMA™ MULTI-CHANNEL VACUUM ULTRAVIOLET (VUV) DETECTOR
Mutagenic impurities, such as nitrosamines are thought to cause DNA mutations, potentially leading to cancer.…
Read More >
Better Living Through (Flavor) Chemistry Part 1 – We Don’t Need No Separation, We Don’t Need No Flow Control
Alex Hodgson, VUV Analytics
Alex describes how GC-VUV is able to differentiate terpene isomers, and why it's possible to…
Read More >
Gas Chromatography with Vacuum Ultraviolet Detection for Pharmaceutical Analysis
LCGC
This Dedicated Dialogue interview with Jinjian Zheng of Merck, Inc. provides his perspective on the…
Read More >Related Reading
Handling Analyte Concentration Differentials with Makeup Gas Pressure Programming For GC-VUV
James Diekmann, VUV Analytics
Makeup gas pressure programming can be used to balance wide analyte concentration differences encountered in gas chromatography, allowing for proper compound identification and quantitative analysis by avoiding spectral saturation.
Read More >
TRACE LEVEL ANALYSIS OF NDMA USING GAS CHROMATOGRAPHY AND THE LUMA™ MULTI-CHANNEL VACUUM ULTRAVIOLET (VUV) DETECTOR
Mutagenic impurities, such as nitrosamines are thought to cause DNA mutations, potentially leading to cancer. Since 2018 there has been a concerted effort by various regulatory bodies i ncluding the ICH and FDA to regulate the average daily intake of nitrosamines in a wide range of drug products. This a dded scrutiny has resulted in...
Read More >
GC-VUV as an Alternate Method to Karl Fischer Titration for Determination of Water in Ketones
Jack Cochran, VUV Analytics
Jack discusses how the GC-VUV alternative method to Karl Fischer titration provides more accurate water determination in ketone solvents.
Read More >