Residual Solvent Analysis – Improving Static Headspace Sampling with Water
Jack Cochran, VUV Analytics
Detectability in static headspace – GC for residual solvent analysis is largely driven by a solvent’s ability to partition from the pharmaceutical ingredient diluent into the…
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Residual Solvent Analysis – Non-Target Analysis
Jack Cochran, VUV Analytics
Our first efforts at doing residual solvent analysis in pharmaceutical products using static headspace – GC-VUV involved the Class 1 and Class 2 compounds specified by…
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Residual Solvent Analysis – No Matrix Effects with the Gerstel MPS2 Static Headspace Autosampler
Jack Cochran, VUV Analytics
Jack explains how no matrix effects were seen during the development of the fast GC-VUV and static headspace method for residual solvent analysis.
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Residual Solvent Analysis – Go with The Flow and Speed Up Your Analyses
Jack Cochran, VUV Analytics
Jack describes how the GC-VUV of residual solvent analysis is an accelerated process. GC runs can be completed in less than 7 minutes, and co-eluting peaks…
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Residual Solvent Analysis – The Lazy Analytical Chemist
Jack Cochran, VUV Analytics
Jack describes how unique VUV spectra enabled the deconvolution of co-eluting analytes that occurred during fast GC-VUV of residual solvent analysis of Class 3 compounds.
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Splitting Up is Not Hard to Do – Configuring Vacuum Ultraviolet Spectroscopy and Mass Spectrometry for Gas Chromatography
Jack Cochran, VUV Analytics
Jack explains how VUV spectroscopy is compatible with mass spectrometry and offers advantages such as isomer differentiation, compound class analysis, and uniform response factors for unknown…
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Simplifying a Complex Sample Matrix….with Spectral Filters!
Alex Hodgson, VUV Analytics
Alex describes the use of spectral filters to analyze compounds in complex matrices such as BHT and benzothiophene in transformer oils.
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Coeluting Peaks and VUV Absorbance Spectra – When a Little Means a Lot
Jack Cochran, VUV Analytics
As a gas chromatographer using MS the coeluting-isomer problem didn’t bother me too much, as it allowed me to practice the art of separation. Inevitably though,…
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Building the VUV Entourage in Terpene Analysis
Jack Cochran, VUV Analytics
Jack describes how GC-VUV is an effective tool for cannabis terpene analysis. Isomer analysis by GC is straightforward and co-eluting peaks are spectrally resolved.
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